Greystone Associates                                                                                                           The Power of Insight   
Home About Greystone News Events Contact
 Drug Delivery: Injectable Drug Delivery (May 2010)

Buy This Research

$3,850

 ¤ Buy Now

  Resources   Report
 Injectable Drug Delivery
 

The past decade has seen a dramatic shift in terms of the types of approved injectable drugs, the diseases they target, and the devices used to deliver them. This shift has fostered change on several levels of the healthcare sector. The injectable drug segment has seen a marked increase in the level of drug/device integration, as prefilled syringes and specialized injection devices proliferate in response to safety and economic challenges posed by recombinant protein drugs, while administration of injectables has moved increasingly from practitioner offices and healthcare facilities to patient homes. This report examines the key therapeutic, product, market and regulatory factors for injectable drugs across ten major disease and therapeutic classes, providing essential insight and forecasts into the implications of this evolving landscape.

Publication Date: May 2010

Summary of Contents

 

Executive Summary

 

Injectable Drugs – The Market Opportunity

 

The Evolving Drug Therapeutics Landscape

Injectable Drug Demand Drivers

    Diseases and Indications

    Patient Demographics

    Developing Economies

Market Factors

    Managed Care and Healthcare Costs

    Regulations and Regulatory Sentiment      

Technology Drivers

    Drug Stability

    Device Design & Technology

    Patient and Care-giver Sentiment              

    Self-Administration and Patient-friendly Features

 

Commercial Injection Devices – Evolving Development and Usage Trends

 

Syringes

    Traditional Disposables

    Prefilled Syringes

      Glass

      Plastic

      Prefillable Safety Syringes

Autoinjectors

Safety Syringes

Pen Injectors

Needle-free Injectors

Novel Injection Devices

 

Injectable Drug Therapeutics – Technology Factors

 

Formulation Factors

    Biological Drug Stability

    Sustained Release Formulations

    Lyophilization and Reconstitution

Growth of Prefilled Syringes

    Partnerships and Alliances

        PFS Manufacturing

        Fill-and-Finish Operations

    Device Selection Factors

        Drug-Device Compatibility

        Luer vs Fixed Needle

Customized injection Devices

    Cost vs Competitive Advantage

    Branding/Product Differentiation Opportunities

 

Injectable Drug Therapeutics – Market Factors

 

Regulatory Factors and Issues

    FDA Regulations

        FDA Guidance

        Regulating Combination Products

    Sharps Legislations

        Growth and Diversity of Safety Syringes

        Sharps Disposal

Clinical Trial Factors

Managed Care and Healthcare Economics
 

Injectable Drug Therapeutics – Segment Assessments and Forecasts

 

Anemia

    Recent Changes in the Injectables Landscape

    Chemotherapy Continue to Drive Demand

    Forecasts and Outlook                                   

Anticoagulants

    Lovenox Continues to Dominate Segment

    Prefilled Syringes Predominate

    Key Demand Drivers and Sustainability        

    Forecasts and Outlook

Growth Hormone Deficiency

    Single-Digit Growth Intensifies Competition

    The Impact of New Products

    High-end Injection Devices and Product Branding

    Forecasts and Outlook

Hepatitis

    Limitations of Interferon Therapy

    Side Effects and Patient Compliance

    Combination Therapies in the Pipeline

    Therapeutic Demand Factors                         

    Forecasts and Outlook

Inflammatory Autoimmune Diseases

    Growth of TNF Inhibitors Remains Strong

    Expanded Indications and Earlier Use

    Recent Approvals Cloud Competitive Picture

    Numerous Alternative Immune Factors in the Pipeline

    Forecasts and Outlook

Osteoporosis

    An Unmet Need and a Growing Market

    Favorable Demographics Drive Therapeutic Demand

    Product Life Cycle Factors and Competing Dosage Forms      

    Forecasts and Outlook

Multiple Sclerosis

    Biologicals Improve Patient QOL

    Copaxone vs the Cytokines

    Therapeutic Focus Remains on RRMS

    Device Strategies and Self-Administration

    Forecasts and Outlook

Reproductive Medicine

    Segment Analysis, Product Assessments & Market Factors

    Device Ease-of-Use and Patient Compliance

    Therapeutic Demand                                      

    Forecasts and Outlook

Vaccines

    Prophylactic Vaccines

        Prefilled Syringe-to-Vial Ratio Increasing

        Extending Childhood Vaccines to Poor Economies

        Branded Seasonal Vaccines Increase

        Forecasts and Outlook

    Therapeutic Vaccines

        Near-Term Disease Targets

        Long-Term Potential

        Forecasts and Outlook

 

 

Profiles of Market Participants

 
About Our Reports

Our reports are carefully researched and written to provide timely and insightful analysis of key factors and developments shaping the commercial marketplace. The focused nature of our publications is designed to allow readers to identify emerging demand and growth opportunities in selected markets. Numerous charts, tables and graphs complement the text, with evaluations and assessments of current and probable future market developments, technology issues and business factors - information necessary to compete effectively in the global marketplace.