Molecular Imaging Agents Technologies Targets and Commercial Prospects

Driven by advances in molecular probe design and biomarker detection methodologies, new imaging agents that can improve visualization of pathologies and cellular processes are changing the practice of diagnostic medicine. The ability of this new generation of contrast agents to detect metabolic changes at the molecular level has significant potential for improving visualization and quality of care. Targetable and activatable imaging agents are gaining interest for a wide range of diagnostic applications that include cardiology, neurology and soft tissue tumor detection. The number of healthcare conditions that can be effectively imaged noninvasively is expanding as a result of these innovative detection technologies. Targeted and activatable imaging agents offer a unique capability to generate unambiguous images by exploiting specific molecular targets, pathways or cellular processes. This new wave of imaging agents signals a paradigm shift in which the reagents take on new importance.

Publication Date: July 2010

Summary of Contents

Executive Summary

Advanced Imaging Agents - Market Dynamics

Targeted Therapy

The Potential of Physiological Imaging

Molecular Imaging – Current Successes

Market Drivers

Industry Alignment and Competitive Landscape

Differential Diagnosis

Diagnostic Imaging Technology

Candidates and Strategies

Antibodies

Conjugated Radioisotopes

Lanthanide Chelates

Metabolic Biomarkers

Optical Probes

Nanoparticles

Targeted Imaging Agents

Activatable Imaging Agents

Leading Academic/Research Programs/Centers

Imaging Modalities & the Potential of Molecular Imaging

MRI

Optical Imaging

PET

SPECT

Ultrasound

The Need for New Imaging Agents

Disease Detection

Image-Guided Drug Delivery

Physiological Process Mapping

Therapeutic Screening

Treatment Assessment

Clinical Applications –Near-Term Assessment and Future Impact

Physiological Visualization

Angiogenesis

Apoptosis

Inflammation

Disease Detection and Therapeutic Management

Autoimmunity

Cardiology

Neurology

Oncology

Market Factors

Guidance, Rules and Regulations

Clinical Validation

Alliances & Partnerships

Complementary Imaging Modalities and Hybrid Systems

Company Profiles

About Our Reports

Our reports are carefully researched and written to provide timely and insightful analysis of key factors and developments shaping the commercial marketplace. The focused nature of our publications is designed to allow readers to identify emerging demand and growth opportunities in selected markets. Numerous charts, tables and graphs complement the text, with evaluations and assessments of current and probable future market developments, technology issues and business factors - information necessary to compete effectively in the global marketplace.